C45h56n7o9p Guanosin, 5 '-o- [4-Methodioryl) Phenylmtyl] -2' methyl- (2-methyl- n- (2-methyl-

C45h56n7o -9p Guanosin, 5 '-o- [4-Methohoder) Phenylmthyl)

Basis Informatioun:

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Promrat Detail

Produktiounsnagéieren

Stoff Detail

Fas Registry Nummer

150780-67-9

H303

Schlëssel kierperlech Eegeschafte	Wäert	Bedingchmëttel
Molekular Gewiicht	869.94	-
pka (virausgesot)	9.16 ± 0,20	Meescht sauer Tempo: 25 ° C

Aner Nimm an Identifizéierer

N # CCCOP (OC1C (CC (N2C = NC = 3C (= C5) C6 = CC = C (OC) C) CC32) CC) C) C) C) C) C) C) C) C) C) C) C.

Isomeresch Laachen

C (oc) c (= o) n = c (nc (c (c) c) c (c) c) 3 (cc = cc = cc = o1) (o1c3 = c (n = n = c2) c (= = C = C4) (C5 = CC = C (OC) C = C5) C6 = CC = CC = C6

Inchi

Inchi = 1s / c45h56n7o -9p / C1-28 (2) 41 (53) 39-48-48-40-37 (53,7--25-19

46) 59 (3) 30.8-22-35 (60-43) 26-59-45 (34-12-12-15,32-15/12-15-3,7-310.2-15-31-15-3,7-3,7-35) 52 (3) 36-35 (60-43) 26-59-45 (34-12-12-15/12-15-3,7-310.2-15-310.2-15-31-15-3,7-3,7-3- -Wonn -3,36,38-39.43h, 13,25-26h2h2,1-h3, (H28,509.53,53,53-, 38---, 38--, 38--,38.30.3,3,36,38-383h, 13,25-26h2h2.1h3, (H28.48.50,53.53 )-, 38---, 3,58,58,5,00,00,00,30,30,30,30.30.30,3,3,36,38-383h, 13,25-26h2h2,1h3, (H28.48.53,53-, 38-

Inchi Schlëssel

Irrdhzuoznwdj-mlldkzsosa-n

1 aneren Numm fir dës Substanz

Guanosin, 5 '-O- [BIS (4-Joretixophyl) Phenylmthyl] -2 '-O-Methyl-N- (2-Methyl-1-oxopropyl) -, 3 '- [2-cyanethyl Bis (1 methylylhoder) Phosphoder)

Experimentell Spektre

Spektre verfügbar
13 c nmr
Hetero nmr

Virausgesot Eegeschafte

Eegeschafte verfügbar
Biologesch
Chemeschen
Lipinski
Struktur verbonnen

Biologesch

Prowalange	Wäert	Bedingchmëttel	Quellatioun
BIKOCONSENTRATIOUN FIELD	183	pH 1; Temp: 25 ° C	(1) ACD
BIKOCONSENTRATIOUN FIELD	38990	pH 2; Temp: 25 ° C	(1) ACD
BIKOCONSENTRATIOUN FIELD	355500	pH 3; Temp: 25 ° C	(1) ACD
BIKOCONSENTRATIOUN FIELD	1.08 x 105	pH 4; Temp: 25 ° C	(1) ACD
BIKOCONSENTRATIOUN FIELD	1.36 x 105	pH 5; Temp: 25 ° C	(1) ACD
BIKOCONSENTRATIOUN FIELD	1.39 X 105	pH 6; Temp: 25 ° C	(1) ACD
BIKOCONSENTRATIOUN FIELD	1.38 x 105	pH 7; Temp: 25 ° C	(1) ACD
BIKOCONSENTRATIOUN FIELD	1.24 X 105	pH 8; Temp: 25 ° C	(1) ACD
BIKOCONSENTRATIOUN FIELD	6360000	pH 9; Temp: 25 ° C	(1) ACD
BIKOCONSENTRATIOUN FIELD	11900	ph 10; Temp: 25 ° C	(1) ACD

Chemeschen

Prowalange	Wäert	Bedingchmëttel	Quellatioun
Kokéieren	220	pH 1; Temp: 25 ° C	(1) ACD
Kokéieren	4680	pH 2; Temp: 25 ° C	(1) ACD
Kokéieren	42600	pH 3; Temp: 25 ° C	(1) ACD
Kokéieren	1.30 x 105	pH 4; Temp: 25 ° C	(1) ACD
Kokéieren	1.63 x 105	pH 5; Temp: 25 ° C	(1) ACD
Kokéieren	1.67 x 105	pH 6; Temp: 25 ° C	(1) ACD
Kokéieren	1,65 x 105	pH 7; Temp: 25 ° C	(1) ACD
Kokéieren	1.49 X 105	pH 8; Temp: 25 ° C	(1) ACD

Prowalange	Wäert	Bedingchmëttel	Quellatioun
Kokéieren	76400	pH 9; Temp: 25 ° C	(1) ACD
Kokéieren	14200	ph 10; Temp: 25 ° C	(1) ACD
Aloggenlogt	4.19	pH 1; Temp: 25 ° C	(1) ACD
Aloggenlogt	5.52	pH 2; Temp: 25 ° C	(1) ACD
Aloggenlogt	6.48	pH 3; Temp: 25 ° C	(1) ACD
Aloggenlogt	6.966	pH 4; Temp: 25 ° C	(1) ACD
Aloggenlogt	7.06	pH 5; Temp: 25 ° C	(1) ACD
Aloggenlogt	7.07	pH 6; Temp: 25 ° C	(1) ACD
Aloggenlogt	7.07	pH 7; Temp: 25 ° C	(1) ACD
Aloggenlogt	7.02	pH 8; Temp: 25 ° C	(1) ACD
Aloggenlogt	6.73	pH 9; Temp: 25 ° C	(1) ACD
Aloggenlogt	6.00	ph 10; Temp: 25 ° C	(1) ACD
AloggenO Aloggen	7.072 ± 0.7211	Temp: 25 ° C	(1) ACD
Mass intrinsesch Solubilitéit	1.2 x 10-4 g / l	Temp: 25 ° C	(1) ACD
Massebelibilitéit	0,096 g / l	pH 1; Temp: 25 ° C	(1) ACD
Massebelibilitéit	4.3 x 10-3 g / l	pH 2; Temp: 25 ° C	(1) ACD
Massebelibilitéit	4.8 x 10-4 g / l	pH 3; Temp: 25 ° C	(1) ACD
Massebelibilitéit	1.6 x 10-4 g / l	pH 4; Temp: 25 ° C	(1) ACD
Massebelibilitéit	1.2 x 10-4 g / l	pH 5; Temp: 25 ° C	(1) ACD
Massebelibilitéit	1.2 x 10-4 g / l	pH 6; Temp: 25 ° C	(1) ACD
Massebelibilitéit	1.2 x 10-4 g / l	pH 7; Temp: 25 ° C	(1) ACD
Massebelibilitéit	1.4 x 10-4 g / l	pH 8; Temp: 25 ° C	(1) ACD
Massebelibilitéit	2.7 x 10-4 g / l	pH 9; Temp: 25 ° C	(1) ACD
Massebelibilitéit	1.4 x 10-3 g / l	ph 10; Temp: 25 ° C	(1) ACD
Massebelibilitéit	1.2 x 10-4 g / l	Ongebrach Waasser ph 7.00; Temp: 25 ° C	(1) ACD
Molar intrinsesch Solubilitéit	1.4 x 10-7 Mol / l	Temp: 25 ° C	(1) ACD
Molar sublabilitéit	1.1 x 10-4 Mol / l	pH 1; Temp: 25 ° C	(1) ACD
Molar sublabilitéit	5.0 x 10-6 MOL / L	pH 2; Temp: 25 ° C	(1) ACD
Molar sublabilitéit	5.5 x 10-7 MOL / L	pH 3; Temp: 25 ° C	(1) ACD
Molar sublabilitéit	1,8 x 10-7 mol / l	pH 4; Temp: 25 ° C	(1) ACD
Molar sublabilitéit	1.4 x 10-7 Mol / l	pH 5; Temp: 25 ° C	(1) ACD
Molar sublabilitéit	1.4 x 10-7 Mol / l	pH 6; Temp: 25 ° C	(1) ACD

Prowalange	Wäert	Bedingchmëttel	Quellatioun
Molar sublabilitéit	1.4 x 10-7 Mol / l	pH 7; Temp: 25 ° C	(1) ACD
Molar sublabilitéit	1.6 X 10-7 MOL / L	pH 8; Temp: 25 ° C	(1) ACD
Molar sublabilitéit	3.1 x 10-7 MOL / L	pH 9; Temp: 25 ° C	(1) ACD
Molar sublabilitéit	1.6 X 10-6 MOL / L	ph 10; Temp: 25 ° C	(1) ACD
Molar sublabilitéit	1.4 x 10-7 Mol / l	Ongebrach Waasser ph 7.00; Temp: 25 ° C	(1) ACD
Molekular Gewiicht	869.94
paka	9.16 ± 0,20	Meescht sauer Tempo: 25 ° C	(1) ACD
paka	3.45 ± 0.70	Déi meescht Basis Tempo: 25 ° C	(1) ACD

Lipinski

Prowalange	Wäert	Bedingchmëttel	Quellatioun
Fräi rotativ Obligatiounen	19		(1) ACD
H Akzeptoren	16		(1) ACD
H Donateuren	2		(1) ACD
H Spender / Acceptor Zomm	18		(1) ACD
AloggenO Aloggen	7.072 ± 0.7211	Temp: 25 ° C	(1) ACD
Molekular Gewiicht	869.94